2xkc
From Proteopedia
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STRUCTURE OF NEK2 BOUND TO AMINOPYRAZINE COMPOUND 14
Template:ABSTRACT PUBMED 20936789
About this Structure
2xkc is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Whelligan DK, Solanki S, Taylor D, Thomson DW, Cheung KM, Boxall K, Mas-Droux C, Barillari C, Burns S, Grummitt CG, Collins I, van Montfort RL, Aherne GW, Bayliss R, Hoelder S. Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: SAR and Structural Characterization. J Med Chem. 2010 Oct 11. PMID:20936789 doi:10.1021/jm1008727
