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3i68

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[[Image:3i68.png|left|200px]]
 
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{{STRUCTURE_3i68| PDB=3i68 | SCENE= }}
{{STRUCTURE_3i68| PDB=3i68 | SCENE= }}
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===Plasmodium falciparum dihydroorotate dehydrogenase bound with triazolopyrimidine-based inhibitor DSM2===
===Plasmodium falciparum dihydroorotate dehydrogenase bound with triazolopyrimidine-based inhibitor DSM2===
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{{ABSTRACT_PUBMED_19640844}}
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==Function==
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[[http://www.uniprot.org/uniprot/PYRD_PLAF7 PYRD_PLAF7]] Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
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{{ABSTRACT_PUBMED_19640844}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:019640844</ref><references group="xtra"/>
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<ref group="xtra">PMID:019640844</ref><references group="xtra"/><references/>
[[Category: Dihydroorotate oxidase]]
[[Category: Dihydroorotate oxidase]]
[[Category: Plasmodium falciparum 3d7]]
[[Category: Plasmodium falciparum 3d7]]

Revision as of 09:19, 27 March 2013

Template:STRUCTURE 3i68

Contents

Plasmodium falciparum dihydroorotate dehydrogenase bound with triazolopyrimidine-based inhibitor DSM2

Template:ABSTRACT PUBMED 19640844

Function

[PYRD_PLAF7] Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.

About this Structure

3i68 is a 1 chain structure with sequence from Plasmodium falciparum 3d7. Full crystallographic information is available from OCA.

Reference

  • Deng X, Gujjar R, El Mazouni F, Kaminsky W, Malmquist NA, Goldsmith EJ, Rathod PK, Phillips MA. Structural plasticity of malaria dihydroorotate dehydrogenase allows selective binding of diverse chemical scaffolds. J Biol Chem. 2009 Sep 25;284(39):26999-7009. Epub 2009 Jul 28. PMID:19640844 doi:10.1074/jbc.M109.028589

Proteopedia Page Contributors and Editors (what is this?)

OCA

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