2yk2

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m (Protected "2yk2" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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[[Image:2yk2.png|left|200px]]
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The entry 2yk2 is ON HOLD
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{{STRUCTURE_2yk2| PDB=2yk2 | SCENE= }}
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Authors: Vallee, F., Carrez, C., Pilorge, F., Dupuy, A., Parent, A., Bertin, L., Thompson, F., Ferrari, P., Fassy, F., Lamberton, A., Thomas, A., Arrebola, R., Guerif, S., Rohaut, A., Certal, V., Ruxer, J.M., Delorme, C., Jouanen, A., Dumas, J., Grepin, C., Combeau, C., Goulaouic, H., Dereu, N., Mikol, V., Mailliet, P., Minoux, H.
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===TRICYCLIC SERIES OF HSP90 INHIBITORS===
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Description: Tricyclic series of Hsp90 inhibitors
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{{ABSTRACT_PUBMED_21972823}}
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==About this Structure==
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[[2yk2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YK2 OCA].
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==Reference==
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<ref group="xtra">PMID:021972823</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Dupuy, A.]]
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[[Category: Vallee, F.]]
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[[Category: Chaperone]]
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[[Category: Inhibition]]

Revision as of 10:10, 30 October 2011

Image:2yk2.png

Template:STRUCTURE 2yk2

TRICYCLIC SERIES OF HSP90 INHIBITORS

Template:ABSTRACT PUBMED 21972823

About this Structure

2yk2 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Vallee F, Carrez C, Pilorge F, Dupuy A, Parent A, Bertin L, Thompson F, Ferrari P, Fassy F, Lamberton A, Thomas A, Arrebola R, Guerif S, Rohaut A, Certal V, Ruxer JM, Delorme C, Jouanen A, Dumas J, Grepin C, Combeau C, Goulaouic H, Dereu N, Mikol V, Mailliet P, Minoux H. Tricyclic Series of Heat Shock Protein 90 (Hsp90) Inhibitors Part I: Discovery of Tricyclic Imidazo[4,5-c]pyridines as Potent Inhibitors of the Hsp90 Molecular Chaperone. J Med Chem. 2011 Oct 27;54(20):7206-19. Epub 2011 Oct 5. PMID:21972823 doi:10.1021/jm200784m

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OCA

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