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3n7a

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[[Image:3n7a.png|left|200px]]
 
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{{STRUCTURE_3n7a| PDB=3n7a | SCENE= }}
{{STRUCTURE_3n7a| PDB=3n7a | SCENE= }}
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===Crystal structure of 3-dehydroquinate dehydratase from Mycobacterium tuberculosis in complex with inhibitor 2===
===Crystal structure of 3-dehydroquinate dehydratase from Mycobacterium tuberculosis in complex with inhibitor 2===
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{{ABSTRACT_PUBMED_21410435}}
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==Function==
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[[http://www.uniprot.org/uniprot/AROQ_MYCTU AROQ_MYCTU]] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]
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{{ABSTRACT_PUBMED_21410435}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:021410435</ref><references group="xtra"/>
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<ref group="xtra">PMID:021410435</ref><references group="xtra"/><references/>
[[Category: 3-dehydroquinate dehydratase]]
[[Category: 3-dehydroquinate dehydratase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]

Revision as of 21:00, 17 April 2013

Template:STRUCTURE 3n7a

Contents

Crystal structure of 3-dehydroquinate dehydratase from Mycobacterium tuberculosis in complex with inhibitor 2

Template:ABSTRACT PUBMED 21410435

Function

[AROQ_MYCTU] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]

About this Structure

3n7a is a 24 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  • Dias MV, Snee WC, Bromfield KM, Payne R, Palaninathan SK, Ciulli A, Howard NI, Abell C, Sacchettini JC, Blundell TL. Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis. Biochem J. 2011 Mar 17. PMID:21410435 doi:10.1042/BJ20110002

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OCA

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