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3r92

From Proteopedia

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[[Image:3r92.jpg|left|200px]]
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[[Image:3r92.png|left|200px]]
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{{STRUCTURE_3r92| PDB=3r92 | SCENE= }}
{{STRUCTURE_3r92| PDB=3r92 | SCENE= }}
===Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model.===
===Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model.===
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{{ABSTRACT_PUBMED_21605975}}
{{ABSTRACT_PUBMED_21605975}}
==About this Structure==
==About this Structure==
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[[3r92]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R92 OCA].
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[[3r92]] is a 1 chain structure of [[Heat Shock Proteins]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R92 OCA].
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==See Also==
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*[[Heat Shock Proteins|Heat Shock Proteins]]
==Reference==
==Reference==

Revision as of 16:52, 26 July 2012

Image:3r92.png

Template:STRUCTURE 3r92

Contents

Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model.

Template:ABSTRACT PUBMED 21605975

About this Structure

3r92 is a 1 chain structure of Heat Shock Proteins with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Zapf CW, Bloom JD, McBean JL, Dushin RG, Golas JM, Liu H, Lucas J, Boschelli F, Vogan E, Levin JI. Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3627-31. Epub 2011 Apr 28. PMID:21605975 doi:10.1016/j.bmcl.2011.04.102

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