3s3v

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'''Unreleased structure'''
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[[Image:3s3v.jpg|left|200px]]
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The entry 3s3v is ON HOLD
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{{STRUCTURE_3s3v| PDB=3s3v | SCENE= }}
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Authors: Cody, V., Pace, J., Piraino, J., Queener, S.F.
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===human dihydrofolate reductase Q35K/N64F double mutant binary complex with trimethoprim===
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Description: human dihydrofolate reductase Q35K/N64F double mutant binary complex with trimethoprim
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{{ABSTRACT_PUBMED_21684339}}
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==About this Structure==
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[[3s3v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S3V OCA].
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==Reference==
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<ref group="xtra">PMID:021684339</ref><references group="xtra"/>
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[[Category: Dihydrofolate reductase]]
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[[Category: Homo sapiens]]
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[[Category: Cody, V.]]
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[[Category: Pace, J.]]
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[[Category: Piraino, J.]]
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[[Category: Queener, S F.]]
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[[Category: Novel second binding site]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]

Revision as of 05:33, 28 September 2011

Image:3s3v.jpg

Template:STRUCTURE 3s3v

human dihydrofolate reductase Q35K/N64F double mutant binary complex with trimethoprim

Template:ABSTRACT PUBMED 21684339

About this Structure

3s3v is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Cody V, Pace J, Piraino J, Queener SF. Crystallographic analysis reveals a novel second binding site for trimethoprim in active site double mutants of human dihydrofolate reductase. J Struct Biol. 2011 Oct;176(1):52-9. Epub 2011 Jun 13. PMID:21684339 doi:10.1016/j.jsb.2011.06.001

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OCA

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