3pnb
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_3pnb| PDB=3pnb | SCENE= }} | {{STRUCTURE_3pnb| PDB=3pnb | SCENE= }} | ||
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===Phosphopantetheine Adenylyltransferase from Mycobacterium tuberculosis in complex with coenzyme A=== | ===Phosphopantetheine Adenylyltransferase from Mycobacterium tuberculosis in complex with coenzyme A=== | ||
+ | {{ABSTRACT_PUBMED_21543857}} | ||
- | + | ==Function== | |
- | + | [[http://www.uniprot.org/uniprot/COAD_MYCTU COAD_MYCTU]] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity). | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID:021543857</ref><references group="xtra"/> | + | <ref group="xtra">PMID:021543857</ref><references group="xtra"/><references/> |
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Pantetheine-phosphate adenylyltransferase]] | [[Category: Pantetheine-phosphate adenylyltransferase]] |
Revision as of 08:14, 8 May 2013
Contents |
Phosphopantetheine Adenylyltransferase from Mycobacterium tuberculosis in complex with coenzyme A
Template:ABSTRACT PUBMED 21543857
Function
[COAD_MYCTU] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity).
About this Structure
3pnb is a 4 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Wubben T, Mesecar AD. Structure of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase in complex with the feedback inhibitor CoA reveals only one active-site conformation. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 May 1;67(Pt, 5):541-5. Epub 2011 Apr 20. PMID:21543857 doi:10.1107/S1744309111010761