User:User:Marcia Ivonne Peña Paz
From Proteopedia
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Brain and muscle Arnt like 1. Also known as MOP3 | Brain and muscle Arnt like 1. Also known as MOP3 | ||
| - | <Structure load='==Your Heading Here (maybe something like 'Structure')==<StructureSection load='1dq8' size='500' side='right' caption='Structure of HMG-CoA reductase (PDB entry [[1dq8]])' scene=''>2KDK</StructureSection>' size='500' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | ||
| - | + | <Structure load='2KDK' size='500' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | |
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It is part of the transcriptional/translational feed back loop of the circadian timing system. It forms an heterodimer with CLOCK or NPAS2 and both translocate into the nucleus. | It is part of the transcriptional/translational feed back loop of the circadian timing system. It forms an heterodimer with CLOCK or NPAS2 and both translocate into the nucleus. | ||
The heterodimer binds to E-box promoter elements of target genes. It modulates the expression of the genes ''cry'', ''per'', ''dbp'', ''ror'', ''ppara'', ''namt'', ''ccg'', ''myod'', cki. | The heterodimer binds to E-box promoter elements of target genes. It modulates the expression of the genes ''cry'', ''per'', ''dbp'', ''ror'', ''ppara'', ''namt'', ''ccg'', ''myod'', cki. | ||
Revision as of 14:43, 23 June 2011
BMAL_1
Brain and muscle Arnt like 1. Also known as MOP3
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It is part of the transcriptional/translational feed back loop of the circadian timing system. It forms an heterodimer with CLOCK or NPAS2 and both translocate into the nucleus. The heterodimer binds to E-box promoter elements of target genes. It modulates the expression of the genes cry, per, dbp, ror, ppara, namt, ccg, myod, cki.
