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3ril
From Proteopedia
(Difference between revisions)
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| - | + | [[Image:3ril.jpg|left|200px]] | |
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| + | The line below this paragraph, containing "STRUCTURE_3ril", creates the "Structure Box" on the page. | ||
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| + | {{STRUCTURE_3ril| PDB=3ril | SCENE= }} | ||
| - | + | ===The acid beta-glucosidase active site exhibits plasticity in binding 3,4,5,6-tetrahydroxyazepane-based inhibitors: implications for pharmacological chaperone design for gaucher disease=== | |
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_22047104}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 22047104 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_22047104}} | ||
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| + | ==About this Structure== | ||
| + | [[3ril]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RIL OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022047104</ref><references group="xtra"/> | ||
| + | [[Category: Glucosylceramidase]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Lieberman, R L.]] | ||
| + | [[Category: Orwig, S D.]] | ||
| + | [[Category: Glycosylation]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
| + | [[Category: Lysosomal hydrolase]] | ||
| + | [[Category: Lysosome]] | ||
| + | [[Category: Tim-barrel]] | ||
Revision as of 06:38, 14 March 2012
The acid beta-glucosidase active site exhibits plasticity in binding 3,4,5,6-tetrahydroxyazepane-based inhibitors: implications for pharmacological chaperone design for gaucher disease
Template:ABSTRACT PUBMED 22047104
About this Structure
3ril is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Orwig SD, Tan YL, Grimster NP, Yu Z, Powers ET, Kelly JW, Lieberman RL. Binding of 3,4,5,6-tetrahydroxyazepanes to the acid-beta-glucosidase active site: implications for pharmacological chaperone design for Gaucher disease. Biochemistry. 2011 Dec 13;50(49):10647-57. Epub 2011 Nov 14. PMID:22047104 doi:10.1021/bi201619z
