3sfc

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'''Unreleased structure'''
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[[Image:3sfc.jpg|left|200px]]
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The entry 3sfc is ON HOLD until Paper Publication
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{{STRUCTURE_3sfc| PDB=3sfc | SCENE= }}
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Authors: Scheiper, B., Matter, H., Steinhagen, H, Bocskei, Z., Fleury, V., McCort, G.
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===Structure-Based Optimization of Potent 4- and 6-Azaindole-3-Carboxamides as Renin Inhibitors===
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Description: Structure-Based Optimization of Potent 4-and 6-Azaindole-3-Carboxamides as Renin Inhibitors
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{{ABSTRACT_PUBMED_21840218}}
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==About this Structure==
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[[3sfc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SFC OCA].
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==Reference==
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<ref group="xtra">PMID:021840218</ref><ref group="xtra">PMID:020850300</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Renin]]
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[[Category: Bocskei, Z.]]
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[[Category: Fleury, V.]]
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[[Category: Matter, H.]]
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[[Category: McCort, G.]]
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[[Category: Scheiper, B.]]
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[[Category: Steinhagen, H]]
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[[Category: Aspartyl protease]]
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[[Category: Beta barrel]]
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[[Category: Extracellular space]]
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[[Category: Glycosylation]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Hypertension]]
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[[Category: Pepsin-like protease]]
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[[Category: Renin human]]
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[[Category: Renin inhibition]]

Revision as of 06:50, 31 August 2011

Image:3sfc.jpg

Template:STRUCTURE 3sfc

Structure-Based Optimization of Potent 4- and 6-Azaindole-3-Carboxamides as Renin Inhibitors

Template:ABSTRACT PUBMED 21840218

About this Structure

3sfc is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Scheiper B, Matter H, Steinhagen H, Bocskei Z, Fleury V, McCort G. Structure-based optimization of potent 4- and 6-azaindole-3-carboxamides as renin inhibitors. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5480-6. Epub 2011 Jul 6. PMID:21840218 doi:10.1016/j.bmcl.2011.06.114
  • Scheiper B, Matter H, Steinhagen H, Stilz U, Bocskei Z, Fleury V, McCort G. Discovery and optimization of a new class of potent and non-chiral indole-3-carboxamide-based renin inhibitors. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6268-72. Epub 2010 Aug 21. PMID:20850300 doi:10.1016/j.bmcl.2010.08.092

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OCA

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