We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
Group:MUZIC:Nebulin
From Proteopedia
(Difference between revisions)
| Line 4: | Line 4: | ||
==Function== | ==Function== | ||
| - | + | The Nebulin protein is involved in the structural integrity of the sarcomeres and is linked to many signalling pathways crucial for the maintenance of the sarcomere. | |
| + | The main fucntions of Nebulin are: | ||
| + | - to define and regulate the lenght of the thin filament of actin (molecular ruler) | ||
| + | - to maintain the alignment of adjacent myofibrills (linker of adjacent Z-disks) | ||
| + | - to regulate muscle contraction (regulator of cross-bridge cycles) | ||
----- | ----- | ||
| Line 20: | Line 24: | ||
The Nebulin SH3 domain adopts a ß-Barrel <scene name='User:Marie-Cecile_Pelissier/Workbench/Nebulin/Barrel/2'>fold</scene>. | The Nebulin SH3 domain adopts a ß-Barrel <scene name='User:Marie-Cecile_Pelissier/Workbench/Nebulin/Barrel/2'>fold</scene>. | ||
| - | == | + | ==References== |
Revision as of 12:48, 1 July 2011
Introduction
| |||||||||||
Proteopedia Page Contributors and Editors (what is this?)
Marie-Cecile Pelissier, Michal Harel, Jaime Prilusky, Nikos Pinotsis
