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Group:MUZIC:Nebulin

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The Nebulin protein is involved in the structural integrity of the sarcomeres and is linked to many signalling pathways crucial for the maintenance of the sarcomere.
The Nebulin protein is involved in the structural integrity of the sarcomeres and is linked to many signalling pathways crucial for the maintenance of the sarcomere.
The main fucntions of Nebulin are:
The main fucntions of Nebulin are:
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1.define and regulate the lenght of the thin filament of actin (molecular ruler)
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1. To define and regulate the lenght of the thin filament of actin (molecular ruler);
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2.maintain the alignment of adjacent myofibrills (linker of adjacent Z-disks)
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2. To maintain the alignment of adjacent myofibrills (linker of adjacent Z-disks);
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3.regulate muscle contraction (regulator of cross-bridge cycles)
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3. To regulate muscle contraction (regulator of cross-bridge cycles).
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Revision as of 15:31, 1 July 2011

Introduction

NMR structure of the SH3 domain of Nebulin

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

Marie-Cecile Pelissier, Michal Harel, Jaime Prilusky, Nikos Pinotsis

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