Group:MUZIC:XIN

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== Interactions with other proteins/Function ==
== Interactions with other proteins/Function ==
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Xin and Mena/VASP colocalize with filamin c in [intercalated discs][http://en.wikipedia.org/wiki/Intercalated_disc](ICD, structure at the end of the myocytes that transduce force from the myofibrils via the cell membranes to the extracelluar matrix and neighboring cells) in the adult heart.
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Xin directly binds the EVH1 domain proteins Mena and VASP <ref name="pmid16631741">.
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Xin directly binds the EVH1 domain proteins Mena and VASP and colocalizes with filamin c<ref name="pmid16631741">.
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[ aaaa http://en.wikipedia.org/wiki/Intercalated_disc]

Revision as of 09:31, 10 July 2011

Xin actin-binding repeat-containing protein 1 (Alternative name: Cardiomyopathy-associated protein 1) is coded by the gene (Synonyms:CMYA1, XIN) and has an actin-binding domain (ABD). It crosslinks actin filaments and participates in anchoring of membrane proteins.

Contents

Sequence Annotation

Function

[1]

Interactions with other proteins/Function

Xin and Mena/VASP colocalize with filamin c in [intercalated discs][1](ICD, structure at the end of the myocytes that transduce force from the myofibrils via the cell membranes to the extracelluar matrix and neighboring cells) in the adult heart.

Xin directly binds the EVH1 domain proteins Mena and VASP and colocalizes with filamin c[2]

Proteopedia Page Contributors and Editors (what is this?)

Georg Mlynek, Nikos Pinotsis, Jaime Prilusky

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