Group:MUZIC:XIN
From Proteopedia
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Xin and Mena/VASP colocalize with filamin c in [intercalated discs][http://en.wikipedia.org/wiki/Intercalated_disc](ICD, structure at the end of the myocytes that transduce force from the myofibrils via the cell membranes to the extracelluar matrix and neighboring cells) in the adult heart. | Xin and Mena/VASP colocalize with filamin c in [intercalated discs][http://en.wikipedia.org/wiki/Intercalated_disc](ICD, structure at the end of the myocytes that transduce force from the myofibrils via the cell membranes to the extracelluar matrix and neighboring cells) in the adult heart. | ||
| - | Xin directly binds the EVH1 domain proteins Mena and VASP | + | Xin directly binds the EVH1 domain proteins Mena and VASP <ref name="pmid16631741">. |
| + | Xin binds the unique insertion containing Ig domain 20. | ||
| + | Xin directly binds F-actin <ref name="pmid15454575">. | ||
| - | [ aaaa http://en.wikipedia.org/wiki/Intercalated_disc] | + | hhhh [ aaaa http://en.wikipedia.org/wiki/Intercalated_disc] |
Revision as of 09:37, 10 July 2011
Xin actin-binding repeat-containing protein 1 (Alternative name: Cardiomyopathy-associated protein 1) is coded by the gene (Synonyms:CMYA1, XIN) and has an actin-binding domain (ABD). It crosslinks actin filaments and participates in anchoring of membrane proteins.
Sequence Annotation
Function
Interactions with other proteins/Function
Xin and Mena/VASP colocalize with filamin c in [intercalated discs][1](ICD, structure at the end of the myocytes that transduce force from the myofibrils via the cell membranes to the extracelluar matrix and neighboring cells) in the adult heart.
Xin directly binds the EVH1 domain proteins Mena and VASP [2]
