3sqy

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m (Protected "3sqy" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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[[Image:3sqy.jpg|left|200px]]
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The entry 3sqy is ON HOLD
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{{STRUCTURE_3sqy| PDB=3sqy | SCENE= }}
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Authors: Hilgers, M.
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===S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines===
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Description: S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines
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{{ABSTRACT_PUBMED_21831637}}
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==About this Structure==
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[[3sqy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SQY OCA].
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==Reference==
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<ref group="xtra">PMID:021831637</ref><references group="xtra"/>
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[[Category: Dihydrofolate reductase]]
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[[Category: Staphylococcus aureus]]
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[[Category: Hilgers, M.]]
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[[Category: Dhfr]]
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[[Category: Dihydrofolate reductase]]
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[[Category: Drug design]]
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[[Category: Enzyme inhibitor]]
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[[Category: Folate]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]

Revision as of 06:46, 31 August 2011

Image:3sqy.jpg

Template:STRUCTURE 3sqy

S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines

Template:ABSTRACT PUBMED 21831637

About this Structure

3sqy is a 1 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.

Reference

  • Li X, Hilgers M, Cunningham M, Chen Z, Trzoss M, Zhang J, Kohnen L, Lam T, Creighton C, Gc K, Nelson K, Kwan B, Stidham M, Brown-Driver V, Shaw KJ, Finn J. Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5171-6. Epub 2011 Jul 23. PMID:21831637 doi:10.1016/j.bmcl.2011.07.059

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OCA

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