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3rkz
From Proteopedia
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Revision as of 07:59, 3 August 2011
Discovery of a stable macrocyclic o-aminobenzamide Hsp90 inhibitor capable of significantly decreasing tumor volume in a mouse xenograft model.
Template:ABSTRACT PUBMED 21715165
About this Structure
3rkz is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Zapf CW, Bloom JD, Li Z, Dushin RG, Nittoli T, Otteng M, Nikitenko A, Golas JM, Liu H, Lucas J, Boschelli F, Vogan E, Olland A, Johnson M, Levin JI. Discovery of a stable macrocyclic o-aminobenzamide Hsp90 inhibitor which significantly decreases tumor volume in a mouse xenograft model. Bioorg Med Chem Lett. 2011 Jun 27. PMID:21715165 doi:10.1016/j.bmcl.2011.05.102
Categories: Homo sapiens | Bloom, J D. | Boschelli, F. | Dushin, R G. | Golas, J M. | Johnson, M. | Levin, J I. | Li, Z. | Liu, H. | Lucas, J. | Nikitenko, A. | Nittoli, T. | Olland, A. | Otteng, M. | Vogan, E. | Zapf, C W. | Atp binding domain | Atp-binding | Chaperone | Chaperone-chaperone inhibitor complex | Nucleotide-binding | Phosphoprotein | Stress response
