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Matrix metalloproteinase
From Proteopedia
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| - | {{STRUCTURE_1su3| PDB=1su3 | SIZE=300| SCENE= |right| CAPTION= Human pro MMP1, [[1su3]] }} | + | {{STRUCTURE_1su3| PDB=1su3 | SIZE=300| SCENE= |right| CAPTION= Human pro MMP1 complex with HEPES, sulfate, Ca+2, Cl-1, Na+1, Zn+2 ions, [[1su3]] }} |
'''Matrix metalloproteinases''' (MMP) are Zinc-dependent endopeptidases. MMP degrades extracellular matrix proteins. MMPs are produced by 28 different genes and are classified according to their protein substrates. They are inhibited by proteases called tissue inhibitors of metalloproteinase (TIMP). The pro-MMP contains a pro-peptide which must be removed to render the MMP active. | '''Matrix metalloproteinases''' (MMP) are Zinc-dependent endopeptidases. MMP degrades extracellular matrix proteins. MMPs are produced by 28 different genes and are classified according to their protein substrates. They are inhibited by proteases called tissue inhibitors of metalloproteinase (TIMP). The pro-MMP contains a pro-peptide which must be removed to render the MMP active. | ||
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| - | ==3D structures of | + | ==3D structures of matrix metalloproteinase== |
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Revision as of 07:44, 13 July 2011
Matrix metalloproteinases (MMP) are Zinc-dependent endopeptidases. MMP degrades extracellular matrix proteins. MMPs are produced by 28 different genes and are classified according to their protein substrates. They are inhibited by proteases called tissue inhibitors of metalloproteinase (TIMP). The pro-MMP contains a pro-peptide which must be removed to render the MMP active.
