3qpp
From Proteopedia
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[[Image:3qpp.png|left|200px]] | [[Image:3qpp.png|left|200px]] | ||
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{{STRUCTURE_3qpp| PDB=3qpp | SCENE= }} | {{STRUCTURE_3qpp| PDB=3qpp | SCENE= }} | ||
===Structure of PDE10-inhibitor complex=== | ===Structure of PDE10-inhibitor complex=== | ||
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{{ABSTRACT_PUBMED_21650160}} | {{ABSTRACT_PUBMED_21650160}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3qpp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QPP OCA]. | + | [[3qpp]] is a 1 chain structure of [[Phosphodiesterase]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QPP OCA]. |
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| + | ==See Also== | ||
| + | *[[Phosphodiesterase|Phosphodiesterase]] | ||
==Reference== | ==Reference== | ||
Revision as of 23:12, 26 July 2012
Contents |
Structure of PDE10-inhibitor complex
Template:ABSTRACT PUBMED 21650160
About this Structure
3qpp is a 1 chain structure of Phosphodiesterase with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
See Also
Reference
- Helal CJ, Kang Z, Hou X, Pandit J, Chappie TA, Humphrey JM, Marr ES, Fennell KF, Chenard LK, Fox C, Schmidt CJ, Williams RD, Chapin DS, Siuciak J, Lebel L, Menniti F, Cianfrogna J, Fonseca KR, Nelson FR, O'Connor R, Macdougall M, McDowell L, Liras S. Use of Structure-Based Design to Discover a Potent, Selective, In Vivo Active Phosphodiesterase 10A Inhibitor Lead Series for the Treatment of Schizophrenia. J Med Chem. 2011 Jun 8. PMID:21650160 doi:10.1021/jm2001508
