3sw8

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Revision as of 06:42, 17 August 2011

Template:STRUCTURE 3sw8

Strep Peptide Deformylase with a time dependent dichlorobenzamide-reverse hydroxamic acid

Template:ABSTRACT PUBMED 21711014

About this Structure

3sw8 is a 1 chain structure with sequence from Streptococcus pneumoniae. Full crystallographic information is available from OCA.

Reference

• Totoritis R, Duraiswami C, Taylor AN, Kerrigan JJ, Campobasso N, Ward P, King BW, Murray-Thompson MF, Jones AD, Van Aller G, Aubart KM, Zalacain M, Thrall SH, Meek TD, Schwartz B. Understanding the Origins of Time Dependent Inhibition by Polypeptide Deformylase Inhibitors. Biochemistry. 2011 Jun 28. PMID:21711014 doi:10.1021/bi200655g
• Smith KJ, Petit CM, Aubart K, Smyth M, McManus E, Jones J, Fosberry A, Lewis C, Lonetto M, Christensen SB. Structural variation and inhibitor binding in polypeptide deformylase from four different bacterial species. Protein Sci. 2003 Feb;12(2):349-60. PMID:12538898