3os3
From Proteopedia
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| - | [[Image:3os3. | + | [[Image:3os3.png|left|200px]] |
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{{STRUCTURE_3os3| PDB=3os3 | SCENE= }} | {{STRUCTURE_3os3| PDB=3os3 | SCENE= }} | ||
===Mitogen-activated protein kinase kinase 1 (MEK1) in complex with CH4858061 and MgATP=== | ===Mitogen-activated protein kinase kinase 1 (MEK1) in complex with CH4858061 and MgATP=== | ||
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{{ABSTRACT_PUBMED_21316218}} | {{ABSTRACT_PUBMED_21316218}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3os3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OS3 OCA]. | + | [[3os3]] is a 1 chain structure of [[Mitogen-activated protein kinase kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OS3 OCA]. |
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| + | ==See Also== | ||
| + | *[[Mitogen-activated protein kinase kinase|Mitogen-activated protein kinase kinase]] | ||
==Reference== | ==Reference== | ||
Revision as of 22:17, 26 July 2012
Contents |
Mitogen-activated protein kinase kinase 1 (MEK1) in complex with CH4858061 and MgATP
Template:ABSTRACT PUBMED 21316218
About this Structure
3os3 is a 1 chain structure of Mitogen-activated protein kinase kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Isshiki Y, Kohchi Y, Iikura H, Matsubara Y, Asoh K, Murata T, Kohchi M, Mizuguchi E, Tsujii S, Hattori K, Miura T, Yoshimura Y, Aida S, Miwa M, Saitoh R, Murao N, Okabe H, Belunis C, Janson C, Lukacs C, Schuck V, Shimma N. Design and synthesis of novel allosteric MEK inhibitor CH4987655 as an orally available anticancer agent. Bioorg Med Chem Lett. 2011 Jan 21. PMID:21316218 doi:10.1016/j.bmcl.2011.01.062
