3an4

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Revision as of 06:09, 27 July 2011

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Template:STRUCTURE 3an4

Human PPAR gamma ligand binding domain in complex with a gamma selective agonist MO4R

Template:ABSTRACT PUBMED 21128600

About this Structure

3an4 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Ohashi M, Oyama T, Nakagome I, Satoh M, Nishio Y, Nobusada H, Hirono S, Morikawa K, Hashimoto Y, Miyachi H. Design, Synthesis, and Structural Analysis of Phenylpropanoic Acid-Type PPARgamma-Selective Agonists: Discovery of Reversed Stereochemistry-Activity Relationship. J Med Chem. 2010 Dec 3. PMID:21128600 doi:10.1021/jm101233f