3qlr
From Proteopedia
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===Candida albicans dihydrofolate reductase complexed with NADPH and 6-methyl-5-[(3R)-3-(3,4,5-trimethoxyphenyl)pent-1-yn-1-yl]pyrimidine-2,4-diamine (UCP112A)=== | ===Candida albicans dihydrofolate reductase complexed with NADPH and 6-methyl-5-[(3R)-3-(3,4,5-trimethoxyphenyl)pent-1-yn-1-yl]pyrimidine-2,4-diamine (UCP112A)=== | ||
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{{ABSTRACT_PUBMED_21726415}} | {{ABSTRACT_PUBMED_21726415}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3qlr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3qlr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_11006_[[candida_stellatoidea]] Atcc 11006 [[candida stellatoidea]]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QLR OCA]. |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:021726415</ref><references group="xtra"/> | + | <ref group="xtra">PMID:021726415</ref><references group="xtra"/><references/> |
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[[Category: Anderson, A C.]] | [[Category: Anderson, A C.]] | ||
[[Category: Bendel, S D.]] | [[Category: Bendel, S D.]] | ||
Revision as of 12:24, 20 November 2013
Candida albicans dihydrofolate reductase complexed with NADPH and 6-methyl-5-[(3R)-3-(3,4,5-trimethoxyphenyl)pent-1-yn-1-yl]pyrimidine-2,4-diamine (UCP112A)
Template:ABSTRACT PUBMED 21726415
About this Structure
3qlr is a 2 chain structure with sequence from candida_stellatoidea Atcc 11006 candida stellatoidea. Full crystallographic information is available from OCA.
Reference
- Paulsen JL, Bendel SD, Anderson AC. Crystal structures of Candida albicans dihydrofolate reductase bound to propargyl-linked antifolates reveal the flexibility of active site loop residues critical for ligand potency and selectivity. Chem Biol Drug Des. 2011 Jul 5. doi: 10.1111/j.1747-0285.2011.01169.x. PMID:21726415 doi:10.1111/j.1747-0285.2011.01169.x
