3qly

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[[Image:3qly.png|left|200px]]
 
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{{STRUCTURE_3qly| PDB=3qly | SCENE= }}
{{STRUCTURE_3qly| PDB=3qly | SCENE= }}
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===Candida glabrata dihydrofolate reductase complexed with NADPH and 6-methyl-5-[3-methyl-3-(3,4,5-trimethoxyphenyl)but-1-yn-1-yl]pyrimidine-2,4-diamine (UCP115A)===
===Candida glabrata dihydrofolate reductase complexed with NADPH and 6-methyl-5-[3-methyl-3-(3,4,5-trimethoxyphenyl)but-1-yn-1-yl]pyrimidine-2,4-diamine (UCP115A)===
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{{ABSTRACT_PUBMED_21726415}}
{{ABSTRACT_PUBMED_21726415}}
==About this Structure==
==About this Structure==
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[[3qly]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Candida_glabrata Candida glabrata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QLY OCA].
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[[3qly]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_2001 Atcc 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QLY OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:021726415</ref><references group="xtra"/>
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<ref group="xtra">PMID:021726415</ref><references group="xtra"/><references/>
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[[Category: Candida glabrata]]
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[[Category: Atcc 2001]]
[[Category: Anderson, A C.]]
[[Category: Anderson, A C.]]
[[Category: Bendel, S D.]]
[[Category: Bendel, S D.]]

Revision as of 12:14, 20 November 2013

Template:STRUCTURE 3qly

Candida glabrata dihydrofolate reductase complexed with NADPH and 6-methyl-5-[3-methyl-3-(3,4,5-trimethoxyphenyl)but-1-yn-1-yl]pyrimidine-2,4-diamine (UCP115A)

Template:ABSTRACT PUBMED 21726415

About this Structure

3qly is a 2 chain structure with sequence from Atcc 2001. Full crystallographic information is available from OCA.

Reference

  • Paulsen JL, Bendel SD, Anderson AC. Crystal structures of Candida albicans dihydrofolate reductase bound to propargyl-linked antifolates reveal the flexibility of active site loop residues critical for ligand potency and selectivity. Chem Biol Drug Des. 2011 Jul 5. doi: 10.1111/j.1747-0285.2011.01169.x. PMID:21726415 doi:10.1111/j.1747-0285.2011.01169.x

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