3rkz
From Proteopedia
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[[Image:3rkz.png|left|200px]] | [[Image:3rkz.png|left|200px]] | ||
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{{STRUCTURE_3rkz| PDB=3rkz | SCENE= }} | {{STRUCTURE_3rkz| PDB=3rkz | SCENE= }} | ||
===Discovery of a stable macrocyclic o-aminobenzamide Hsp90 inhibitor capable of significantly decreasing tumor volume in a mouse xenograft model.=== | ===Discovery of a stable macrocyclic o-aminobenzamide Hsp90 inhibitor capable of significantly decreasing tumor volume in a mouse xenograft model.=== | ||
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{{ABSTRACT_PUBMED_21715165}} | {{ABSTRACT_PUBMED_21715165}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3rkz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RKZ OCA]. | + | [[3rkz]] is a 1 chain structure of [[Heat Shock Proteins]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RKZ OCA]. |
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| + | ==See Also== | ||
| + | *[[Heat Shock Proteins|Heat Shock Proteins]] | ||
==Reference== | ==Reference== | ||
Revision as of 07:43, 27 July 2012
Contents |
Discovery of a stable macrocyclic o-aminobenzamide Hsp90 inhibitor capable of significantly decreasing tumor volume in a mouse xenograft model.
Template:ABSTRACT PUBMED 21715165
About this Structure
3rkz is a 1 chain structure of Heat Shock Proteins with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Zapf CW, Bloom JD, Li Z, Dushin RG, Nittoli T, Otteng M, Nikitenko A, Golas JM, Liu H, Lucas J, Boschelli F, Vogan E, Olland A, Johnson M, Levin JI. Discovery of a stable macrocyclic o-aminobenzamide Hsp90 inhibitor which significantly decreases tumor volume in a mouse xenograft model. Bioorg Med Chem Lett. 2011 Jun 27. PMID:21715165 doi:10.1016/j.bmcl.2011.05.102
Categories: Homo sapiens | Bloom, J D. | Boschelli, F. | Dushin, R G. | Golas, J M. | Johnson, M. | Levin, J I. | Li, Z. | Liu, H. | Lucas, J. | Nikitenko, A. | Nittoli, T. | Olland, A. | Otteng, M. | Vogan, E. | Zapf, C W. | Atp binding domain | Atp-binding | Chaperone | Chaperone-chaperone inhibitor complex | Nucleotide-binding | Phosphoprotein | Stress response
