3s54

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'''Unreleased structure'''
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[[Image:3s54.jpg|left|200px]]
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The entry 3s54 is ON HOLD until Paper Publication
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{{STRUCTURE_3s54| PDB=3s54 | SCENE= }}
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Authors: Tie, Y.-F., Wang, Y.-F., Weber, I.T.
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===HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P21212===
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Description: HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P21212
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{{ABSTRACT_PUBMED_22238126}}
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==About this Structure==
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[[3s54]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S54 OCA].
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==Reference==
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<ref group="xtra">PMID:022238126</ref><references group="xtra"/>
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[[Category: HIV-1 retropepsin]]
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[[Category: Human immunodeficiency virus 1]]
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[[Category: Tie, Y F.]]
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[[Category: Wang, Y F.]]
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[[Category: Weber, I T.]]
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[[Category: Aspartic protease]]
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[[Category: Darunavir]]
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[[Category: Drug resistance]]
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[[Category: Hiv/aid]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Molecular recognition]]

Revision as of 07:37, 21 March 2012

Image:3s54.jpg

Template:STRUCTURE 3s54

HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P21212

Template:ABSTRACT PUBMED 22238126

About this Structure

3s54 is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Tie Y, Wang YF, Boross PI, Chiu TY, Ghosh AK, Tozser J, Louis JM, Harrison RW, Weber IT. Critical differences in HIV-1 and HIV-2 protease specificity for clinical inhibitors. Protein Sci. 2012 Mar;21(3):339-50. doi: 10.1002/pro.2019. Epub 2012 Jan 24. PMID:22238126 doi:10.1002/pro.2019

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OCA

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