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3st5

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'''Unreleased structure'''
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[[Image:3st5.jpg|left|200px]]
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The entry 3st5 is ON HOLD until Paper Publication
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{{STRUCTURE_3st5| PDB=3st5 | SCENE= }}
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Authors: Wang, Y.-F., Agniswamy, J., Weber, I.T.
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===Crystal structure of wild-type HIV-1 protease with C3-Substituted Hexahydrocyclopentafuranyl Urethane as P2-Ligand, GRL-0489A===
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Description: Crystal structure of wild-type HIV-1 protease with C3-Substituted Hexahydrocyclopentafuranyl Urethane as P2-Ligand, GRL-0489A
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{{ABSTRACT_PUBMED_21800876}}
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==About this Structure==
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[[3st5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ST5 OCA].
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==Reference==
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<ref group="xtra">PMID:021800876</ref><references group="xtra"/>
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[[Category: HIV-1 retropepsin]]
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[[Category: Human immunodeficiency virus 1]]
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[[Category: Agniswamy, J.]]
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[[Category: Wang, Y F.]]
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[[Category: Weber, I T.]]
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[[Category: Aspartic acid protease]]
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[[Category: C3-substituted hexahydrocyclopentafuranyl urethane as p2-ligand]]
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[[Category: Hiv-1 protease inhibitor grl-0489a]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]

Revision as of 06:16, 17 August 2011

Image:3st5.jpg

Template:STRUCTURE 3st5

Crystal structure of wild-type HIV-1 protease with C3-Substituted Hexahydrocyclopentafuranyl Urethane as P2-Ligand, GRL-0489A

Template:ABSTRACT PUBMED 21800876

About this Structure

3st5 is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Ghosh AK, Chapsal BD, Parham GL, Steffey M, Agniswamy J, Wang YF, Amano M, Weber IT, Mitsuya H. Design of HIV-1 Protease Inhibitors with C3-Substituted Hexahydrocyclopentafuranyl Urethanes as P2-Ligands: Synthesis, Biological Evaluation, and Protein-Ligand X-ray Crystal Structure. J Med Chem. 2011 Jul 29. PMID:21800876 doi:10.1021/jm200649p

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OCA

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