3t3c

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-	'''Unreleased structure'''	+	[[Image:3t3c.jpg|left|200px]]
-	The entry 3t3c is ON HOLD until Paper Publication	+	{{STRUCTURE_3t3c| PDB=3t3c | SCENE= }}
-	Authors: Rezacova, P., Kozisek, M., Konvalinka, J., Grantz Saskova, K.	+	===Structure of HIV PR resistant patient derived mutant (comprising 22 mutations) in complex with DRV===
-	Description: Structure of HIV PR resistant patient derived mutant (comprising 22 mutations) in complex with DRV	+	{{ABSTRACT_PUBMED_22644035}}
		+
		+	==About this Structure==
		+	[[3t3c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T3C OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022644035</ref><references group="xtra"/>
		+	[[Category: HIV-1 retropepsin]]
		+	[[Category: Human immunodeficiency virus 1]]
		+	[[Category: Konvalinka, J.]]
		+	[[Category: Kozisek, M.]]
		+	[[Category: Rezacova, P.]]
		+	[[Category: Saskova, K G.]]
		+	[[Category: Hydrolase]]
		+	[[Category: Peptidase]]
		+	[[Category: Viral particle]]

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Revision as of 07:42, 20 June 2012

Template:STRUCTURE 3t3c

Structure of HIV PR resistant patient derived mutant (comprising 22 mutations) in complex with DRV

Template:ABSTRACT PUBMED 22644035

About this Structure

3t3c is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

• Kozisek M, Henke S, Saskova KG, Jacobs GB, Schuch A, Buchholz B, Muller V, Krausslich HG, Rezacova P, Konvalinka J, Bodem J. Mutations in HIV-1 gag and pol compensate for the loss of viral fitness caused by a highly mutated protease. Antimicrob Agents Chemother. 2012 May 29. PMID:22644035 doi:10.1128/AAC.00465-12