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2y3y
From Proteopedia
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| - | [[ | + | ==HOLO-NI(II) HPNIKR IS A SYMMETRIC TETRAMER CONTAINING FOUR CANONIC SQUARE-PLANAR NI(II) IONS AT PHYSIOLOGICAL PH== |
| + | <StructureSection load='2y3y' size='340' side='right' caption='[[2y3y]], [[Resolution|resolution]] 2.39Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2y3y]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori_g27 Helicobacter pylori g27] and [http://en.wikipedia.org/wiki/Unidentified Unidentified]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3Y OCA]. <br> | ||
| + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene><br> | ||
| + | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2caj|2caj]], [[2wvb|2wvb]], [[2wvd|2wvd]], [[2ca9|2ca9]], [[2wve|2wve]], [[2wvf|2wvf]], [[2wvc|2wvc]], [[2cad|2cad]]</td></tr> | ||
| + | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr> | ||
| + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y3y RCSB], [http://www.ebi.ac.uk/pdbsum/2y3y PDBsum]</span></td></tr> | ||
| + | <table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The crystal structure of Helicobacter pylori holo-NikR, a Ni(2+)-dependent transcription factor, determined at pH 7.3, shows four square-planar nickel-binding sites, involving one cysteinate and three histidine ligands. This observation reconciles previous inconsistencies among calorimetric data, structural information at non-physiological pH, and computational studies. | ||
| - | + | Holo-Ni(2+)Helicobacter pylori NikR contains four square-planar nickel-binding sites at physiological pH.,Benini S, Cianci M, Ciurli S Dalton Trans. 2011 Aug 21;40(31):7831-3. Epub 2011 Jul 4. PMID:21725560<ref>PMID:21725560</ref> | |
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| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | == References == | |
| - | + | <references/> | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
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| - | == | + | |
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[[Category: Helicobacter pylori g27]] | [[Category: Helicobacter pylori g27]] | ||
[[Category: Unidentified]] | [[Category: Unidentified]] | ||
Revision as of 07:50, 14 May 2014
HOLO-NI(II) HPNIKR IS A SYMMETRIC TETRAMER CONTAINING FOUR CANONIC SQUARE-PLANAR NI(II) IONS AT PHYSIOLOGICAL PH
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