Pre-mRNA-splicing factor

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== 3D Structures of pre-mRNA splicing factors ==
== 3D Structures of pre-mRNA splicing factors ==
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===Pre-mRNA-splicing factor 2===
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[[3beg]] – hPrp residues 105-219 + Ser/Thr-protein kinase – human<BR />
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[[2o3d]] – hPrp P33 subunit
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===Pre-mRNA-splicing factor 3===
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[[1x4q]] – hPrp PWI domain]] - NMR<BR />
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===Pre-mRNA-splicing factor 3B===
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[[3lqv]], [[2f9d]], [[2f9j]] – hPrp residues 377-415 + pre-mRNA branch site protein 14<BR />
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[[2fho]] - hPrp residues 379-424 + spliceosomal protein P14 - NMR<BR />
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[[2do5]] – hPrp subunit 2 – NMR<BR />
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[[1x5t]] - hPrp subunit 4 – NMR<BR />
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[[1x5u]] - hPrp subunit 4 RNA-binding domain – NMR<BR />
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===Pre-mRNA-splicing factor 8===
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[[3sbt]] – yPrp RNAseH like domain + A1 cistron-splicing factor AAR2 – yeast<BR />
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[[3e66]] – yPrp β-finger domain<BR />
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[[3e9o]], [[3e9p]] - yPrp RNA-binding domain<BR />
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[[2p87]], [[2og4]] - yPrp C terminal<BR />
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[[3lru]] – hPrp residues 1831-1990<BR />
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[[3e9l]] – hPrp endonuclease domain<BR />
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[[3enb]] - hPrp core domain IV<BR />
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[[2p8r]] – Prp C terminal (mutant) – Caenorhabditis elegans
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===Pre-mRNA-splicing factor 18===
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[[2dk4]] – hPrp splicing factor motif domain - NMR<BR />
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===Pre-mRNA-splicing factor 19===
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[[3lrv]] – yPrp WD40 domain<BR />
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[[2bay]] – yPrp U-box<BR />
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[[1n87]] - yPrp U-box - NMR<BR />
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===Pre-mRNA-splicing factor 20===
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[[2i2y]] – Prp RNA-binding domain + RNA – Streptococcus – NMR<BR />
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[[2i38]] - hPrp RNA-binding domain (mutant) – NMR<BR />
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===snRNA-associated-splicing factor 24===
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[[2l9w]] – yPrp C terminal – NMR<BR />
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[[2kh9]] – yPrp residues 115-197 + RNA – NMR<BR />
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[[2go9]] – yPrp RNA-binding domains – NMR<BR />
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[[2ghp]] - yPrp RNA-binding domains
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===Pre-mRNA-splicing factor 43P===
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[[2xau]], [[3kx2 – yPrp + ADP
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===Pre-mRNA-splicing factor RBM22===
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[[2ytc]] – yPrp RNA-binding domain]] - NMR<BR />
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===Pre-mRNA-splicing factor RDS3===
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[[2k0a]] – yPrp - NMR<BR />
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===Pre-mRNA-splicing factor URN1===
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[[2juc]] – yPrp FF domain - NMR<BR />
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[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 08:31, 22 August 2011

Template:STRUCTURE 3e9l

Pre-mRNA-splicing factors (Prp) are the proteins which associate with mRNA at its various splicing sites to produce alternative splicing.

3D Structures of pre-mRNA splicing factors

Pre-mRNA-splicing factor 2

3beg – hPrp residues 105-219 + Ser/Thr-protein kinase – human
2o3d – hPrp P33 subunit

Pre-mRNA-splicing factor 3

1x4q – hPrp PWI domain]] - NMR

Pre-mRNA-splicing factor 3B

3lqv, 2f9d, 2f9j – hPrp residues 377-415 + pre-mRNA branch site protein 14
2fho - hPrp residues 379-424 + spliceosomal protein P14 - NMR
2do5 – hPrp subunit 2 – NMR
1x5t - hPrp subunit 4 – NMR
1x5u - hPrp subunit 4 RNA-binding domain – NMR

Pre-mRNA-splicing factor 8

3sbt – yPrp RNAseH like domain + A1 cistron-splicing factor AAR2 – yeast
3e66 – yPrp β-finger domain
3e9o, 3e9p - yPrp RNA-binding domain
2p87, 2og4 - yPrp C terminal
3lru – hPrp residues 1831-1990
3e9l – hPrp endonuclease domain
3enb - hPrp core domain IV
2p8r – Prp C terminal (mutant) – Caenorhabditis elegans

Pre-mRNA-splicing factor 18

2dk4 – hPrp splicing factor motif domain - NMR

Pre-mRNA-splicing factor 19

3lrv – yPrp WD40 domain
2bay – yPrp U-box
1n87 - yPrp U-box - NMR

Pre-mRNA-splicing factor 20

2i2y – Prp RNA-binding domain + RNA – Streptococcus – NMR
2i38 - hPrp RNA-binding domain (mutant) – NMR

snRNA-associated-splicing factor 24

2l9w – yPrp C terminal – NMR
2kh9 – yPrp residues 115-197 + RNA – NMR
2go9 – yPrp RNA-binding domains – NMR
2ghp - yPrp RNA-binding domains

Pre-mRNA-splicing factor 43P

2xau, [[3kx2 – yPrp + ADP

Pre-mRNA-splicing factor RBM22

2ytc – yPrp RNA-binding domain]] - NMR


Pre-mRNA-splicing factor RDS3

2k0a – yPrp - NMR

Pre-mRNA-splicing factor URN1

2juc – yPrp FF domain - NMR

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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