2cfo

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[[Image:2cfo.png|left|200px]]
 
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{{STRUCTURE_2cfo| PDB=2cfo | SCENE= }}
{{STRUCTURE_2cfo| PDB=2cfo | SCENE= }}
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===NON-DISCRIMINATING GLUTAMYL-TRNA SYNTHETASE FROM THERMOSYNECHOCOCCUS ELONGATUS IN COMPLEX WITH GLU===
===NON-DISCRIMINATING GLUTAMYL-TRNA SYNTHETASE FROM THERMOSYNECHOCOCCUS ELONGATUS IN COMPLEX WITH GLU===
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{{ABSTRACT_PUBMED_16876193}}
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==Function==
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[[http://www.uniprot.org/uniprot/SYE_THEEB SYE_THEEB]] Non-discriminating glutamyl-tRNA synthetase. Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). Acylates both tRNA(Glu) and tRNA(Gln) with glutamate, but has 13-fold higher efficiency with tRNA(Glu).<ref>PMID:16876193</ref>
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{{ABSTRACT_PUBMED_16876193}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:016876193</ref><references group="xtra"/>
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<ref group="xtra">PMID:016876193</ref><references group="xtra"/><references/>
[[Category: Glutamate--tRNA ligase]]
[[Category: Glutamate--tRNA ligase]]
[[Category: Synechococcus elongatus]]
[[Category: Synechococcus elongatus]]

Revision as of 08:42, 23 April 2014

Template:STRUCTURE 2cfo

Contents

NON-DISCRIMINATING GLUTAMYL-TRNA SYNTHETASE FROM THERMOSYNECHOCOCCUS ELONGATUS IN COMPLEX WITH GLU

Template:ABSTRACT PUBMED 16876193

Function

[SYE_THEEB] Non-discriminating glutamyl-tRNA synthetase. Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). Acylates both tRNA(Glu) and tRNA(Gln) with glutamate, but has 13-fold higher efficiency with tRNA(Glu).[1]

About this Structure

2cfo is a 2 chain structure with sequence from Synechococcus elongatus. Full crystallographic information is available from OCA.

Reference

  • Schulze JO, Masoumi A, Nickel D, Jahn M, Jahn D, Schubert WD, Heinz DW. Crystal structure of a non-discriminating glutamyl-tRNA synthetase. J Mol Biol. 2006 Sep 1;361(5):888-97. Epub 2006 Jul 5. PMID:16876193 doi:10.1016/j.jmb.2006.06.054
  1. ↑ Schulze JO, Masoumi A, Nickel D, Jahn M, Jahn D, Schubert WD, Heinz DW. Crystal structure of a non-discriminating glutamyl-tRNA synthetase. J Mol Biol. 2006 Sep 1;361(5):888-97. Epub 2006 Jul 5. PMID:16876193 doi:10.1016/j.jmb.2006.06.054

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OCA

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