3zxh

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'''Unreleased structure'''
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[[Image:3zxh.png|left|200px]]
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The entry 3zxh is ON HOLD until Paper Publication
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{{STRUCTURE_3zxh| PDB=3zxh | SCENE= }}
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Authors: Clark, K.L., Kulathila, R.
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===MMP-13 COMPLEXED WITH 2-NAPTHYLSULFONAMIDE HYDROXAMIC ACID INHIBITOR===
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Description: MMP-13 complexed with 2-Napthylsulfonamide hydroxamic acid inhibitor
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{{ABSTRACT_PUBMED_21937229}}
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==About this Structure==
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[[3zxh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZXH OCA].
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==Reference==
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<ref group="xtra">PMID:021937229</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Clark, K L.]]
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[[Category: Kulathila, R.]]
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[[Category: Carboxylate inhibitor]]
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[[Category: Collagen degradation]]
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[[Category: Extracellular matrix]]
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[[Category: Hydrolase]]
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[[Category: Metal-binding]]
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[[Category: Metallo-enzyme]]
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[[Category: Metalloprotease]]

Revision as of 08:10, 30 October 2011

Image:3zxh.png

Template:STRUCTURE 3zxh

MMP-13 COMPLEXED WITH 2-NAPTHYLSULFONAMIDE HYDROXAMIC ACID INHIBITOR

Template:ABSTRACT PUBMED 21937229

About this Structure

3zxh is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Tommasi RA, Weiler S, McQuire LW, Rogel O, Chambers M, Clark K, Doughty J, Fang J, Ganu V, Grob J, Goldberg R, Goldstein R, Lavoie S, Kulathila R, Macchia W, Melton R, Springer C, Walker M, Zhang J, Zhu L, Shultz M. Potent and selective 2-naphthylsulfonamide substituted hydroxamic acid inhibitors of matrix metalloproteinase-13. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6440-5. Epub 2011 Aug 27. PMID:21937229 doi:10.1016/j.bmcl.2011.08.087

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OCA

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