1ikv
From Proteopedia
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[[Image:1ikv.png|left|200px]] | [[Image:1ikv.png|left|200px]] | ||
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{{STRUCTURE_1ikv| PDB=1ikv | SCENE= }} | {{STRUCTURE_1ikv| PDB=1ikv | SCENE= }} | ||
===K103N Mutant HIV-1 Reverse Transcriptase in Complex with Efivarenz=== | ===K103N Mutant HIV-1 Reverse Transcriptase in Complex with Efivarenz=== | ||
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==See Also== | ==See Also== | ||
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==Reference== | ==Reference== | ||
Revision as of 04:26, 18 July 2012
Contents |
K103N Mutant HIV-1 Reverse Transcriptase in Complex with Efivarenz
Template:ABSTRACT PUBMED 11895437
About this Structure
1ikv is a 2 chain structure of Reverse transcriptase with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
See Also
Reference
- Lindberg J, Sigurdsson S, Lowgren S, Andersson HO, Sahlberg C, Noreen R, Fridborg K, Zhang H, Unge T. Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant. Eur J Biochem. 2002 Mar;269(6):1670-7. PMID:11895437
- Udier-Blagovic M, Tirado-Rives J, Jorgensen WL. Structural and energetic analyses of the effects of the K103N mutation of HIV-1 reverse transcriptase on efavirenz analogues. J Med Chem. 2004 Apr 22;47(9):2389-92. PMID:15084137 doi:10.1021/jm0303507
