3sc1

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'''Unreleased structure'''
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[[Image:3sc1.png|left|200px]]
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The entry 3sc1 is ON HOLD
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{{STRUCTURE_3sc1| PDB=3sc1 | SCENE= }}
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Authors: Greasley, S.E., Ferre, R.-A., Krauss, M., Cronin, C.
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===Novel Isoquinolone PDK1 Inhibitors Discovered through Fragment-Based Lead Discovery===
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Description: Novel Isoquinolone PDK1 Inhibitors Discovered through Fragment-Based Lead Discovery
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{{ABSTRACT_PUBMED_21779981}}
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==About this Structure==
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[[3sc1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SC1 OCA].
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==Reference==
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<ref group="xtra">PMID:021779981</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Cronin, C.]]
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[[Category: Ferre, R A.]]
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[[Category: Greasley, S E.]]
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[[Category: Krauss, M.]]
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[[Category: Kinase domain]]
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[[Category: Phosphoserine]]
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[[Category: Sep]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 09:20, 30 October 2011

Template:STRUCTURE 3sc1

Novel Isoquinolone PDK1 Inhibitors Discovered through Fragment-Based Lead Discovery

Template:ABSTRACT PUBMED 21779981

About this Structure

3sc1 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Johnson MC, Hu Q, Lingardo L, Ferre RA, Greasley S, Yan J, Kath J, Chen P, Ermolieff J, Alton G. Novel isoquinolone PDK1 inhibitors discovered through fragment-based lead discovery. J Comput Aided Mol Des. 2011 Jul;25(7):689-98. Epub 2011 Jul 22. PMID:21779981 doi:10.1007/s10822-011-9456-7

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