3t3p
From Proteopedia
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| - | + | [[Image:3t3p.jpg|left|200px]] | |
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| + | The line below this paragraph, containing "STRUCTURE_3t3p", creates the "Structure Box" on the page. | ||
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| + | {{STRUCTURE_3t3p| PDB=3t3p | SCENE= }} | ||
| - | + | ===A Novel High Affinity Integrin alphaIIbbeta3 Receptor Antagonist That Unexpectedly Displaces Mg2+ from the beta3 MIDAS=== | |
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_22422993}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 22422993 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_22422993}} | ||
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| + | ==About this Structure== | ||
| + | [[3t3p]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T3P OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022422993</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Springer, T A.]] | ||
| + | [[Category: Zhu, J.]] | ||
| + | [[Category: Blood clotting]] | ||
| + | [[Category: Cell adhesion]] | ||
| + | [[Category: Fibrinogen]] | ||
| + | [[Category: Integrin]] | ||
| + | [[Category: Platelet]] | ||
Revision as of 07:41, 28 March 2012
A Novel High Affinity Integrin alphaIIbbeta3 Receptor Antagonist That Unexpectedly Displaces Mg2+ from the beta3 MIDAS
Template:ABSTRACT PUBMED 22422993
About this Structure
3t3p is a 8 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.
Reference
- Zhu J, Choi WS, McCoy JG, Negri A, Zhu J, Naini S, Li J, Shen M, Huang W, Bougie D, Rasmussen M, Aster R, Thomas CJ, Filizola M, Springer TA, Coller BS. Structure-Guided Design of a High-Affinity Platelet Integrin alphaIIbbeta3 Receptor Antagonist That Disrupts Mg2+ Binding to the MIDAS. Sci Transl Med. 2012 Mar 14;4(125):125ra32. PMID:22422993 doi:10.1126/scitranslmed.3003576
