3tkd

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'''Unreleased structure'''
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[[Image:3tkd.jpg|left|200px]]
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The entry 3tkd is ON HOLD
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{{STRUCTURE_3tkd| PDB=3tkd | SCENE= }}
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Authors: Krintel, C., Frydenvang, K., Gajhede, M., Kastrup, J.S.
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===Crystal structure of the GluA2 ligand-binding domain (S1S2J-L483Y-N754S) in complex with glutamate and cyclothiazide at 1.45 A resolution===
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Description: Crystal structure of the GLUA2 ligand-binding domain (S1S2J-L483Y-N754S) in complex with glutamate and cyclothiazide at 1.45 A resolution
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{{ABSTRACT_PUBMED_21895609}}
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==About this Structure==
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[[3tkd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TKD OCA].
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==Reference==
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<ref group="xtra">PMID:021895609</ref><ref group="xtra">PMID:012015593</ref><references group="xtra"/>
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[[Category: Rattus norvegicus]]
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[[Category: Frydenvang, K.]]
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[[Category: Gajhede, M.]]
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[[Category: Kastrup, J S.]]
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[[Category: Krintel, C.]]
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[[Category: Allosteric modulation]]
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[[Category: Ampa receptor ligand-binding domain]]
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[[Category: Cyclothiazide]]
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[[Category: Glua2 s1s2j-l483y-n754]]
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[[Category: Membrane protein]]

Revision as of 06:01, 21 September 2011

Image:3tkd.jpg

Template:STRUCTURE 3tkd

Crystal structure of the GluA2 ligand-binding domain (S1S2J-L483Y-N754S) in complex with glutamate and cyclothiazide at 1.45 A resolution

Template:ABSTRACT PUBMED 21895609

About this Structure

3tkd is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Krintel C, Frydenvang K, Olsen L, Kristensen MT, de Barrios O, Naur P, Francotte P, Pirotte B, Gajhede M, Kastrup JS. Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2. Biochem J. 2011 Sep 7. PMID:21895609 doi:10.1042/BJ20111221
  • Sun Y, Olson R, Horning M, Armstrong N, Mayer M, Gouaux E. Mechanism of glutamate receptor desensitization. Nature. 2002 May 16;417(6886):245-53. PMID:12015593 doi:10.1038/417245a

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OCA

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