We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

1gve

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1gve.png|left|200px]]
 
- 
-
<!--
 
-
The line below this paragraph, containing "STRUCTURE_1gve", creates the "Structure Box" on the page.
 
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
 
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
 
-
or leave the SCENE parameter empty for the default display.
 
-
-->
 
{{STRUCTURE_1gve| PDB=1gve | SCENE= }}
{{STRUCTURE_1gve| PDB=1gve | SCENE= }}
- 
===AFLATOXIN ALDEHYDE REDUCTASE (AKR7A1) FROM RAT LIVER===
===AFLATOXIN ALDEHYDE REDUCTASE (AKR7A1) FROM RAT LIVER===
 +
{{ABSTRACT_PUBMED_11839745}}
-
 
+
==Function==
-
<!--
+
[[http://www.uniprot.org/uniprot/ARK73_RAT ARK73_RAT]] Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. Probably involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.<ref>PMID:12071861</ref>
-
The line below this paragraph, {{ABSTRACT_PUBMED_11839745}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 11839745 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_11839745}}
+
==About this Structure==
==About this Structure==
Line 22: Line 10:
==Reference==
==Reference==
-
<ref group="xtra">PMID:011839745</ref><ref group="xtra">PMID:008234296</ref><references group="xtra"/>
+
<ref group="xtra">PMID:011839745</ref><references group="xtra"/><references/>
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Brown, E.]]
[[Category: Brown, E.]]

Revision as of 10:32, 16 April 2014

Template:STRUCTURE 1gve

Contents

AFLATOXIN ALDEHYDE REDUCTASE (AKR7A1) FROM RAT LIVER

Template:ABSTRACT PUBMED 11839745

Function

[ARK73_RAT] Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. Probably involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.[1]

About this Structure

1gve is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Kozma E, Brown E, Ellis EM, Lapthorn AJ. The crystal structure of rat liver AKR7A1. A dimeric member of the aldo-keto reductase superfamily. J Biol Chem. 2002 May 3;277(18):16285-93. Epub 2002 Feb 11. PMID:11839745 doi:10.1074/jbc.M110808200
  1. ↑ Kelly VP, Sherratt PJ, Crouch DH, Hayes JD. Novel homodimeric and heterodimeric rat gamma-hydroxybutyrate synthases that associate with the Golgi apparatus define a distinct subclass of aldo-keto reductase 7 family proteins. Biochem J. 2002 Sep 15;366(Pt 3):847-61. PMID:12071861 doi:http://dx.doi.org/10.1042/BJ20020342

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1gve"
Personal tools