3srv
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | [[Image:3srv. | + | [[Image:3srv.png|left|200px]] |
<!-- | <!-- | ||
Revision as of 07:54, 30 October 2011
Crystal structure of spleen tyrosine kinase (SYK) in complex with a diaminopyrimidine carboxamide inhibitor
Template:ABSTRACT PUBMED 21903390
About this Structure
3srv is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Liddle J, Atkinson FL, Barker MD, Carter PS, Curtis NR, Davis RP, Douault C, Dickson MC, Elwes D, Garton NS, Gray M, Hayhow TG, Hobbs CI, Jones E, Leach S, Leavens K, Lewis HD, McCleary S, Neu M, Patel VK, Preston AG, Ramirez-Molina C, Shipley TJ, Skone PA, Smithers N, Somers DO, Walker AL, Watson RJ, Weingarten GG. Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor. Bioorg Med Chem Lett. 2011 Aug 12. PMID:21903390 doi:10.1016/j.bmcl.2011.07.082
