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3rjm

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Revision as of 05:56, 5 October 2011

Image:3rjm.png

Template:STRUCTURE 3rjm

CASPASE2 IN COMPLEX WITH CHDI LIGAND 33c

Template:ABSTRACT PUBMED 21903398

About this Structure

3rjm is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Maillard MC, Brookfield FA, Courtney SM, Eustache FM, Gemkow MJ, Handel RK, Johnson LC, Johnson PD, Kerry MA, Krieger F, Meniconi M, Munoz-Sanjuan I, Palfrey JJ, Park H, Schaertl S, Taylor MG, Weddell D, Dominguez C. Exploiting differences in caspase-2 and -3 S(2) subsites for selectivity: Structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors. Bioorg Med Chem. 2011 Oct 1;19(19):5833-51. Epub 2011 Aug 16. PMID:21903398 doi:10.1016/j.bmc.2011.08.020

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OCA

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