This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Semaphorin
From Proteopedia
| Line 1: | Line 1: | ||
| - | {{STRUCTURE_3nvn| PDB=3nvn | SIZE=400| SCENE= |right|CAPTION= | + | {{STRUCTURE_3nvn| PDB=3nvn | SIZE=400| SCENE= |right|CAPTION=Glycosylated human semaphorin 7A (grey) complex with plexin-C1 (green) and Ca+2 ion, [[3nvn]] }} |
'''Semaphorin''' (SEMA) are membrane proteins which act as axonal growth guidance molecules. SEMA act as short-range inhibitory signal. There are 8 classes of SEMA numbered 1 to 7 and V (viral). Each class has several subgroups which share similar characteristics. | '''Semaphorin''' (SEMA) are membrane proteins which act as axonal growth guidance molecules. SEMA act as short-range inhibitory signal. There are 8 classes of SEMA numbered 1 to 7 and V (viral). Each class has several subgroups which share similar characteristics. | ||
Revision as of 09:42, 15 November 2012
Template:STRUCTURE 3nvn
Semaphorin (SEMA) are membrane proteins which act as axonal growth guidance molecules. SEMA act as short-range inhibitory signal. There are 8 classes of SEMA numbered 1 to 7 and V (viral). Each class has several subgroups which share similar characteristics.
3D structures of semaphorin
SEMA 3
1q47 – mSEMA 3A – mouse
SEMA 4
1olz – hSEMA 4D extracellular domain – human
3ol2 - hSEMA 4D extracellular domain + plexin-B1
SEMA 6
3afc, 3okw - mSEMA 6A extracellular domain
3al8 - mSEMA 6A + plexin-A2
