Transketolase
From Proteopedia
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| - | + | {{STRUCTURE_2r5n| PDB=2r5n | SIZE=400| SCENE= |right|CAPTION=E. coli transketolase complex with co-factor thiamine diphosphate and ribose-5-phosphate, [[2r5n]] }} | |
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| - | Transketolase (TKT) catalyzes two opposite reactions. The synthesis of sedoheptulose-7-P in the pentose phosphate pathway using thiamine diphosphate (TPP) as co-factor; and the conversion of sedoheptulose-7-P and glyceraldehyde-3-P to aldose and ketose in the Calvin cycle. | + | '''Transketolase''' (TKT) catalyzes two opposite reactions. The synthesis of sedoheptulose-7-P in the pentose phosphate pathway using thiamine diphosphate (TPP) as co-factor; and the conversion of sedoheptulose-7-P and glyceraldehyde-3-P to aldose and ketose in the Calvin cycle. |
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| - | + | == 3D Structures of transketolase == | |
| - | + | [[1trk]] – yTKT – yeast | |
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| - | + | [[1ay0]] – yTKT (mutant) | |
| - | 3m7i, 3m6l – CjTKT + TPP + ribose 5-P | + | [[2e6k]] – TKT – ''Thermus thermophilus'' |
| - | 3m34 - CjTKT + TPP + Ca | + | |
| - | 1ngs - yTKT + TPP + Ca + erythrose-4-P | + | [[3hyl]] – BaTKT – ''Bacillus anthracis'' |
| - | 2r5n – EcTKT + TPP + ribose 5-P | + | |
| - | 2r8o - EcTKT + TPP + xylulose 5-P | + | [[3kom]] – TKT (mutant) – ''Francisella tularensis'' |
| - | 2r8p - EcTKT + TPP + fructose 6-P | + | |
| + | [[3l84]] – CjTKT – ''Campylobacter jejuni'' | ||
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| + | ===Transketolase binary complexes=== | ||
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| + | [[3m49]] – BaTKT + TPP | ||
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| + | [[3mos]], [[3ooy]] – TKT + TPP - human | ||
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| + | [[1tka]], [[1tkb]], [[1tkc]] – yTKT + TPP analog | ||
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| + | [[1gpu]] - yTKT + TPP derivative | ||
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| + | [[1itz]] - TKT + TPP – maize | ||
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| + | [[1qgd]] - EcTKT + TPP – ''Escherichia coli'' | ||
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| + | [[1r9j]] - TKT + TPP – ''Leishmania mexicana'' | ||
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| + | ===Transketolase ternary complexes=== | ||
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| + | [[3m7i]], [[3m6l]] – CjTKT + TPP + ribose 5-P | ||
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| + | [[3m34]] - CjTKT + TPP + Ca | ||
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| + | [[1ngs]] - yTKT + TPP + Ca + erythrose-4-P | ||
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| + | [[2r5n]] – EcTKT + TPP + ribose 5-P | ||
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| + | [[2r8o]] - EcTKT + TPP + xylulose 5-P | ||
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| + | [[2r8p]] - EcTKT + TPP + fructose 6-P | ||
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| + | [[Category:Topic Page]] | ||
Revision as of 16:14, 27 September 2011
Transketolase (TKT) catalyzes two opposite reactions. The synthesis of sedoheptulose-7-P in the pentose phosphate pathway using thiamine diphosphate (TPP) as co-factor; and the conversion of sedoheptulose-7-P and glyceraldehyde-3-P to aldose and ketose in the Calvin cycle.
Contents |
3D Structures of transketolase
1trk – yTKT – yeast
1ay0 – yTKT (mutant)
2e6k – TKT – Thermus thermophilus
3hyl – BaTKT – Bacillus anthracis
3kom – TKT (mutant) – Francisella tularensis
3l84 – CjTKT – Campylobacter jejuni
Transketolase binary complexes
3m49 – BaTKT + TPP
3mos, 3ooy – TKT + TPP - human
1tka, 1tkb, 1tkc – yTKT + TPP analog
1gpu - yTKT + TPP derivative
1itz - TKT + TPP – maize
1qgd - EcTKT + TPP – Escherichia coli
1r9j - TKT + TPP – Leishmania mexicana
Transketolase ternary complexes
3m7i, 3m6l – CjTKT + TPP + ribose 5-P
3m34 - CjTKT + TPP + Ca
1ngs - yTKT + TPP + Ca + erythrose-4-P
2r5n – EcTKT + TPP + ribose 5-P
2r8o - EcTKT + TPP + xylulose 5-P
2r8p - EcTKT + TPP + fructose 6-P
