2xxh
From Proteopedia
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{{STRUCTURE_2xxh| PDB=2xxh | SCENE= }} | {{STRUCTURE_2xxh| PDB=2xxh | SCENE= }} | ||
===CRYSTAL STRUCTURE OF 1-(4-(2-OXO-2-(1-PYRROLIDINYL)ETHYL)PHENYL)-3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOLE IN COMPLEX WITH THE LIGAND BINDING DOMAIN OF THE RAT GLUA2 RECEPTOR AND GLUTAMATE AT 1.5A RESOLUTION.=== | ===CRYSTAL STRUCTURE OF 1-(4-(2-OXO-2-(1-PYRROLIDINYL)ETHYL)PHENYL)-3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOLE IN COMPLEX WITH THE LIGAND BINDING DOMAIN OF THE RAT GLUA2 RECEPTOR AND GLUTAMATE AT 1.5A RESOLUTION.=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Ionotropic Glutamate Receptors]] | + | *[[Ionotropic Glutamate Receptors|Ionotropic Glutamate Receptors]] |
==Reference== | ==Reference== | ||
Revision as of 16:34, 26 July 2012
Contents |
CRYSTAL STRUCTURE OF 1-(4-(2-OXO-2-(1-PYRROLIDINYL)ETHYL)PHENYL)-3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOLE IN COMPLEX WITH THE LIGAND BINDING DOMAIN OF THE RAT GLUA2 RECEPTOR AND GLUTAMATE AT 1.5A RESOLUTION.
Template:ABSTRACT PUBMED 21128618
About this Structure
2xxh is a 3 chain structure of Ionotropic Glutamate Receptors with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
See Also
Reference
- Ward SE, Harries M, Aldegheri L, Austin NE, Ballantine S, Ballini E, Bradley DM, Bax BD, Clarke BP, Harris AJ, Harrison SA, Melarange RA, Mookherjee C, Mosley J, Dal Negro G, Oliosi B, Smith KJ, Thewlis KM, Woollard PM, Yusaf SP. Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of AMPA Receptor Positive Allosteric Modulators. J Med Chem. 2010 Dec 3. PMID:21128618 doi:10.1021/jm100679e
Categories: Rattus norvegicus | Aldegheri, L. | Austin, N E. | Ballantine, S. | Ballini, E. | Bax, B D. | Bradley, D M. | Clarke, B P. | Dalnegro, G. | Harries, M. | Harris, A J. | Harrison, S A. | Melarange, R A. | Mookherjee, C. | Mosley, J. | Oliosi, B. | Smith, K J. | Thewlis, K M. | Ward, S E. | Woollard, P M. | Yusaf, S P. | Ampa receptor ligand-binding core | Ion channel | Transport protein
