1gpz
From Proteopedia
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{{STRUCTURE_1gpz| PDB=1gpz | SCENE= }} | {{STRUCTURE_1gpz| PDB=1gpz | SCENE= }} | ||
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===THE CRYSTAL STRUCTURE OF THE ZYMOGEN CATALYTIC DOMAIN OF COMPLEMENT PROTEASE C1R=== | ===THE CRYSTAL STRUCTURE OF THE ZYMOGEN CATALYTIC DOMAIN OF COMPLEMENT PROTEASE C1R=== | ||
| + | {{ABSTRACT_PUBMED_11823416}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/C1R_HUMAN C1R_HUMAN]] C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:011823416</ref><references group="xtra"/> | + | <ref group="xtra">PMID:011823416</ref><references group="xtra"/><references/> |
[[Category: Complement subcomponent C1r]] | [[Category: Complement subcomponent C1r]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
Revision as of 10:35, 16 April 2014
Contents |
THE CRYSTAL STRUCTURE OF THE ZYMOGEN CATALYTIC DOMAIN OF COMPLEMENT PROTEASE C1R
Template:ABSTRACT PUBMED 11823416
Function
[C1R_HUMAN] C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
About this Structure
1gpz is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Budayova-Spano M, Lacroix M, Thielens NM, Arlaud GJ, Fontecilla-Camps JC, Gaboriaud C. The crystal structure of the zymogen catalytic domain of complement protease C1r reveals that a disruptive mechanical stress is required to trigger activation of the C1 complex. EMBO J. 2002 Feb 1;21(3):231-9. PMID:11823416 doi:10.1093/emboj/21.3.231
