3tu7

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m (Protected "3tu7" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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[[Image:3tu7.png|left|200px]]
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The entry 3tu7 is ON HOLD
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{{STRUCTURE_3tu7| PDB=3tu7 | SCENE= }}
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Authors: Malley, M., Sack, J.
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===Human alpha-thrombin complexed with N-(methylsulfonyl)-D-phenylalanyl-N-((1-carbamimidoyl-4-piperidinyl)methyl)-l-prolinamide (BMS-189664)===
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Description: HUMAN ALPHA-THROMBIN COMPLEXED WITH N-(METHYLSULFONYL)-D-PHENYLALANYL-N-((1-CARBAMIMIDOYL-4-PIPERIDINYL)METHYL)-L-PROLINAMIDE (BMS-189664)
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{{ABSTRACT_PUBMED_11738570}}
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==About this Structure==
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[[3tu7]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TU7 OCA].
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==Reference==
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<ref group="xtra">PMID:011738570</ref><references group="xtra"/>
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[[Category: Hirudo medicinalis]]
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[[Category: Homo sapiens]]
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[[Category: Thrombin]]
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[[Category: Malley, M.]]
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[[Category: Sack, J S.]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Serine protease]]

Revision as of 07:49, 30 October 2011

Template:STRUCTURE 3tu7

Human alpha-thrombin complexed with N-(methylsulfonyl)-D-phenylalanyl-N-((1-carbamimidoyl-4-piperidinyl)methyl)-l-prolinamide (BMS-189664)

Template:ABSTRACT PUBMED 11738570

About this Structure

3tu7 is a 3 chain structure with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Das J, Kimball SD, Hall SE, Han WC, Iwanowicz E, Lin J, Moquin RV, Reid JA, Sack JS, Malley MF, Chang CY, Chong S, Wang-Iverson DB, Roberts DG, Seiler SM, Schumacher WA, Ogletree ML. Molecular design and structure--activity relationships leading to the potent, selective, and orally active thrombin active site inhibitor BMS-189664. Bioorg Med Chem Lett. 2002 Jan 7;12(1):45-9. PMID:11738570

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