2lds

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[[Image:2lds.png|left|200px]]
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==Solution Structure of a Short-chain LaIT1 from the Venom of Scorpion Liocheles australasiae==
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<StructureSection load='2lds' size='340' side='right' caption='[[2lds]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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== Structural highlights ==
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[[2lds]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Liocheles_australasiae Liocheles australasiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LDS OCA]. <br>
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<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
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== Publication Abstract from PubMed ==
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The solution structure of an insecticidal toxin LaIT1, a 36-residue peptide with a unique amino-acid sequence and two disulfide bonds, isolated from the venom of the scorpion Liocheles australasiae was determined by heteronuclear NMR spectroscopy. Structural similarity search showed that LaIT1 exhibits an inhibitory cystine knot (ICK)-like fold, which usually contains three or more disulfide bonds. Mutational analysis has revealed that two Arg residues of LaIT1, Arg(13) and Arg(15), play significant roles in insecticidal activity.
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Solution structure of a short-chain insecticidal toxin LaIT1 from the venom of scorpion Liocheles australasiae.,Horita S, Matsushita N, Kawachi T, Ayabe R, Miyashita M, Miyakawa T, Nakagawa Y, Nagata K, Miyagawa H, Tanokura M Biochem Biophys Res Commun. 2011 Aug 12;411(4):738-44. Epub 2011 Jul 18. PMID:21782787<ref>PMID:21782787</ref>
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The line below this paragraph, containing "STRUCTURE_2lds", creates the "Structure Box" on the page.
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{{STRUCTURE_2lds| PDB=2lds | SCENE= }}
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===Solution Structure of a Short-chain LaIT1 from the Venom of Scorpion Liocheles australasiae===
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_21782787}}, adds the Publication Abstract to the page
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 21782787 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21782787}}
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==About this Structure==
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[[2lds]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Liocheles_australasiae Liocheles australasiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LDS OCA].
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==Reference==
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<ref group="xtra">PMID:021782787</ref><references group="xtra"/>
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[[Category: Liocheles australasiae]]
[[Category: Liocheles australasiae]]
[[Category: Horita, S.]]
[[Category: Horita, S.]]

Revision as of 08:26, 30 April 2014

Solution Structure of a Short-chain LaIT1 from the Venom of Scorpion Liocheles australasiae

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