3u6i
From Proteopedia
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- | + | [[Image:3u6i.jpg|left|200px]] | |
- | The | + | <!-- |
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+ | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
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+ | {{STRUCTURE_3u6i| PDB=3u6i | SCENE= }} | ||
- | + | ===Crystal structure of c-Met in complex with pyrazolone inhibitor 58a=== | |
- | + | ||
+ | ==About this Structure== | ||
+ | [[3u6i]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U6I OCA]. | ||
+ | |||
+ | ==Reference== | ||
+ | <ref group="xtra">PMID:022320327</ref><references group="xtra"/> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Receptor protein-tyrosine kinase]] | ||
+ | [[Category: Bellon, S F.]] | ||
+ | [[Category: Long, A L.]] | ||
+ | [[Category: Whittington, D A.]] | ||
+ | [[Category: Cancer]] | ||
+ | [[Category: Hepatocyte growth factor]] | ||
+ | [[Category: Kinase domain]] | ||
+ | [[Category: Phosphotransferase]] | ||
+ | [[Category: Transferase-transferase inhibitor complex]] |
Revision as of 07:49, 22 February 2012
Crystal structure of c-Met in complex with pyrazolone inhibitor 58a
About this Structure
3u6i is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Liu L, Norman MH, Lee M, Xi N, Siegmund A, Boezio AA, Booker S, Choquette D, D'Angelo ND, Germain J, Yang K, Yang Y, Zhang Y, Bellon SF, Whittington DA, Harmange JC, Dominguez C, Kim TS, Dussault I. Structure-Based Design of Novel Class II c-Met Inhibitors: 2. SAR and Kinase Selectivity Profiles of the Pyrazolone Series. J Med Chem. 2012 Feb 24. PMID:22320327 doi:http://dx.doi.org/10.1021/jm201331s