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4a4m
From Proteopedia
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| - | + | [[Image:4a4m.jpg|left|200px]] | |
| - | The | + | <!-- |
| + | The line below this paragraph, containing "STRUCTURE_4a4m", creates the "Structure Box" on the page. | ||
| + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
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| + | {{STRUCTURE_4a4m| PDB=4a4m | SCENE= }} | ||
| - | + | ===Crystal structure of the light-activated constitutively active N2C, M257Y,D282C rhodopsin mutant in complex with a peptide resembling the C-terminus of the Galpha-protein subunit (GaCT)=== | |
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| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_22198838}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 22198838 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_22198838}} | ||
| + | |||
| + | ==About this Structure== | ||
| + | [[4a4m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A4M OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022198838</ref><ref group="xtra">PMID:017825322</ref><ref group="xtra">PMID:021389983</ref><references group="xtra"/> | ||
| + | [[Category: Bos taurus]] | ||
| + | [[Category: Deupi, X.]] | ||
| + | [[Category: Edwards, P.]] | ||
| + | [[Category: Nickle, B.]] | ||
| + | [[Category: Oprian, D D.]] | ||
| + | [[Category: Schertler, G F.X.]] | ||
| + | [[Category: Singhal, A.]] | ||
| + | [[Category: Standfuss, J.]] | ||
| + | [[Category: G-protein]] | ||
| + | [[Category: G-protein-coupled receptor]] | ||
| + | [[Category: Metarhodopsin-ii]] | ||
| + | [[Category: Signal tansduction]] | ||
| + | [[Category: Signaling protein]] | ||
| + | [[Category: Visual system]] | ||
Revision as of 06:28, 25 January 2012
Crystal structure of the light-activated constitutively active N2C, M257Y,D282C rhodopsin mutant in complex with a peptide resembling the C-terminus of the Galpha-protein subunit (GaCT)
Template:ABSTRACT PUBMED 22198838
About this Structure
4a4m is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
- Deupi X, Edwards P, Singhal A, Nickle B, Oprian D, Schertler G, Standfuss J. Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II. Proc Natl Acad Sci U S A. 2012 Jan 3;109(1):119-24. Epub 2011 Dec 23. PMID:22198838 doi:10.1073/pnas.1114089108
- Standfuss J, Xie G, Edwards PC, Burghammer M, Oprian DD, Schertler GF. Crystal structure of a thermally stable rhodopsin mutant. J Mol Biol. 2007 Oct 5;372(5):1179-88. Epub 2007 Mar 12. PMID:17825322 doi:10.1016/j.jmb.2007.03.007
- Standfuss J, Edwards PC, D'Antona A, Fransen M, Xie G, Oprian DD, Schertler GF. The structural basis of agonist-induced activation in constitutively active rhodopsin. Nature. 2011 Mar 31;471(7340):656-60. Epub 2011 Mar 9. PMID:21389983 doi:10.1038/nature09795
