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3td4
From Proteopedia
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{{STRUCTURE_3td4| PDB=3td4 | SCENE= }} | {{STRUCTURE_3td4| PDB=3td4 | SCENE= }} | ||
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===Crystal structure of OmpA-like domain from Acinetobacter baumannii in complex with diaminopimelate=== | ===Crystal structure of OmpA-like domain from Acinetobacter baumannii in complex with diaminopimelate=== | ||
| + | {{ABSTRACT_PUBMED_21965596}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/OMP38_ACIBA OMP38_ACIBA]] Porin. Induces apoptosis in human laryngeal epithelial HEp-2 cells through caspases-dependent and AIF-dependent pathways. Purified Omp38 enters the cells and localizes to the mitochondria, which leads to a release of proapoptotic molecules such as cytochrome c and AIF (apoptosis-inducing factor).<ref>PMID:16008580</ref> <ref>PMID:9928952</ref> | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:021965596</ref><references group="xtra"/> | + | <ref group="xtra">PMID:021965596</ref><references group="xtra"/><references/> |
[[Category: Acinetobacter baumannii]] | [[Category: Acinetobacter baumannii]] | ||
[[Category: Kim, H Y.]] | [[Category: Kim, H Y.]] | ||
Revision as of 07:14, 30 June 2013
Contents |
Crystal structure of OmpA-like domain from Acinetobacter baumannii in complex with diaminopimelate
Template:ABSTRACT PUBMED 21965596
Function
[OMP38_ACIBA] Porin. Induces apoptosis in human laryngeal epithelial HEp-2 cells through caspases-dependent and AIF-dependent pathways. Purified Omp38 enters the cells and localizes to the mitochondria, which leads to a release of proapoptotic molecules such as cytochrome c and AIF (apoptosis-inducing factor).[1] [2]
About this Structure
3td4 is a 8 chain structure with sequence from Acinetobacter baumannii. Full crystallographic information is available from OCA.
Reference
- Park JS, Lee WC, Yeo KJ, Ryu KS, Kumarasiri M, Hesek D, Lee M, Mobashery S, Song JH, Kim SI, Lee JC, Cheong C, Jeon YH, Kim HY. Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane. FASEB J. 2011 Sep 30. PMID:21965596 doi:10.1096/fj.11-188425
- ↑ Choi CH, Lee EY, Lee YC, Park TI, Kim HJ, Hyun SH, Kim SA, Lee SK, Lee JC. Outer membrane protein 38 of Acinetobacter baumannii localizes to the mitochondria and induces apoptosis of epithelial cells. Cell Microbiol. 2005 Aug;7(8):1127-38. PMID:16008580 doi:CMI538
- ↑ Jyothisri K, Deepak V, Rajeswari MR. Purification and characterization of a major 40 kDa outer membrane protein of Acinetobacter baumannii. FEBS Lett. 1999 Jan 22;443(1):57-60. PMID:9928952
