3au7

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[[Image:3au7.png|left|200px]]
 
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{{STRUCTURE_3au7| PDB=3au7 | SCENE= }}
{{STRUCTURE_3au7| PDB=3au7 | SCENE= }}
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===Crystal structure of the ZRD-deleted mutant of TiaS in complex with agmatine===
===Crystal structure of the ZRD-deleted mutant of TiaS in complex with agmatine===
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{{ABSTRACT_PUBMED_22002223}}
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==Function==
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[[http://www.uniprot.org/uniprot/TIAS_ARCFU TIAS_ARCFU]] ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.<ref>PMID:20139989</ref>
==About this Structure==
==About this Structure==
[[3au7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AU7 OCA].
[[3au7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AU7 OCA].
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==Reference==
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<ref group="xtra">PMID:022002223</ref><references group="xtra"/><references/>
[[Category: Archaeoglobus fulgidus]]
[[Category: Archaeoglobus fulgidus]]
[[Category: Numata, T.]]
[[Category: Numata, T.]]

Revision as of 08:05, 19 June 2013

Template:STRUCTURE 3au7

Contents

Crystal structure of the ZRD-deleted mutant of TiaS in complex with agmatine

Template:ABSTRACT PUBMED 22002223

Function

[TIAS_ARCFU] ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.[1]

About this Structure

3au7 is a 1 chain structure with sequence from Archaeoglobus fulgidus. Full crystallographic information is available from OCA.

Reference

  • Osawa T, Kimura S, Terasaka N, Inanaga H, Suzuki T, Numata T. Structural basis of tRNA agmatinylation essential for AUA codon decoding. Nat Struct Mol Biol. 2011 Oct 16;18(11):1275-80. doi: 10.1038/nsmb.2144. PMID:22002223 doi:10.1038/nsmb.2144
  1. Ikeuchi Y, Kimura S, Numata T, Nakamura D, Yokogawa T, Ogata T, Wada T, Suzuki T, Suzuki T. Agmatine-conjugated cytidine in a tRNA anticodon is essential for AUA decoding in archaea. Nat Chem Biol. 2010 Apr;6(4):277-82. doi: 10.1038/nchembio.323. Epub 2010 Feb 7. PMID:20139989 doi:10.1038/nchembio.323

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