4a5s

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Revision as of 11:23, 9 November 2011 (edit) OCA (Talk | contribs) m (Protected "4a5s" [edit=sysop:move=sysop]) ← Previous diff		Revision as of 06:32, 8 February 2012 (edit) (undo) OCA (Talk | contribs) Next diff →
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-	'''Unreleased structure'''	+	[[Image:4a5s.jpg|left|200px]]
-	The entry 4a5s is ON HOLD	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_4a5s", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_4a5s| PDB=4a5s | SCENE= }}
-	Authors: Ostermann, N., Kroemer, M., Zink, F., Gerhartz, B., Sutton, J.M., Clark, S.E., Dunsdon, S.J., Fenton, G., Fillmore, A., Harris, N.V., Higgs, C., Hurley, C.A., Krintel, S.L., MacKenzie, R.E., Duttaroy, A., Gangl, E., Maniara, W., Sedrani, R., Namoto, K., Sirockin, F., Trappe, J., Hassiepen, U., Baeschlin, D.K.	+	===CRYSTAL STRUCTURE OF HUMAN DPP4 IN COMPLEX WITH A NOVAL HETEROCYCLIC DPP4 INHIBITOR===
-	Description: CRYSTAL STRUCTURE OF HUMAN DPP4 IN COMPLEX WITH A NOVAL HETEROCYCLIC DPP4 INHIBITOR	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22177783}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22177783 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22177783}}
		+
		+	==About this Structure==
		+	[[4a5s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A5S OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022177783</ref><references group="xtra"/>
		+	[[Category: Dipeptidyl-peptidase IV]]
		+	[[Category: Homo sapiens]]
		+	[[Category: Baeschlin, D K.]]
		+	[[Category: Clark, D E.]]
		+	[[Category: Dunsdon, S J.]]
		+	[[Category: Duttaroy, A.]]
		+	[[Category: Fenton, G.]]
		+	[[Category: Fillmore, A.]]
		+	[[Category: Gangl, E.]]
		+	[[Category: Gerhartz, B.]]
		+	[[Category: Harris, N V.]]
		+	[[Category: Hassiepen, U.]]
		+	[[Category: Higgs, C.]]
		+	[[Category: Hurley, C A.]]
		+	[[Category: Krintel, S L.]]
		+	[[Category: Kroemer, M.]]
		+	[[Category: Mackenzie, R E.]]
		+	[[Category: Maniara, W.]]
		+	[[Category: Namoto, K.]]
		+	[[Category: Ostermann, N.]]
		+	[[Category: Sedrani, R.]]
		+	[[Category: Sirockin, F.]]
		+	[[Category: Sutton, J M.]]
		+	[[Category: Trappe, J.]]
		+	[[Category: Zink, F.]]
		+	[[Category: Hydrolase]]
		+	[[Category: Novartis compound nvp-biv988]]
		+	[[Category: Type 2 diabetes]]

---

Revision as of 06:32, 8 February 2012

Template:STRUCTURE 4a5s

CRYSTAL STRUCTURE OF HUMAN DPP4 IN COMPLEX WITH A NOVAL HETEROCYCLIC DPP4 INHIBITOR

Template:ABSTRACT PUBMED 22177783

About this Structure

4a5s is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Sutton JM, Clark DE, Dunsdon SJ, Fenton G, Fillmore A, Harris NV, Higgs C, Hurley CA, Krintel SL, Mackenzie RE, Duttaroy A, Gangl E, Maniara W, Sedrani R, Namoto K, Ostermann N, Gerhartz B, Sirockin F, Trappe J, Hassiepen U, Baeschlin DK. Novel heterocyclic DPP-4 inhibitors for the treatment of type 2 diabetes. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1464-8. Epub 2011 Nov 20. PMID:22177783 doi:10.1016/j.bmcl.2011.11.054