Dynein
From Proteopedia
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[[Image:3fm7.png|left|200px|thumb|Crystal Structure of Dynein, [[3fm7]]]] | [[Image:3fm7.png|left|200px|thumb|Crystal Structure of Dynein, [[3fm7]]]] | ||
| - | {{STRUCTURE_3fm7| PDB=3fm7 | SIZE= | + | {{STRUCTURE_3fm7| PDB=3fm7 | SIZE=400| SCENE=Dynein/Dynein/3 |right| CAPTION=Dynein light and intermediate chains, [[3fm7]] }} |
'''Dynein''' is a motor protein which walks along the microtubule toward its minus end, i.e. it is a minus-end directed motor. Dyneins are classified as cytoplasmic (DYNC) or axonemal. The Dyneins are composed of heavy, intermediate and light chains. For discussion of the DYNC inter mediate and light chains see: [[Dynein light and intermediate chain]]. | '''Dynein''' is a motor protein which walks along the microtubule toward its minus end, i.e. it is a minus-end directed motor. Dyneins are classified as cytoplasmic (DYNC) or axonemal. The Dyneins are composed of heavy, intermediate and light chains. For discussion of the DYNC inter mediate and light chains see: [[Dynein light and intermediate chain]]. | ||
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== 3D Structures of Dynein == | == 3D Structures of Dynein == | ||
| - | ''Update | + | ''Update June 2012'' |
===Dynein light chain=== | ===Dynein light chain=== | ||
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[[1yo3]] – DYNC light chain 1 – ''Plasmodium falciparum''<BR /> | [[1yo3]] – DYNC light chain 1 – ''Plasmodium falciparum''<BR /> | ||
[[1xdx]], [[1m9l]], [[1ds9]] - CrDYNC light chain TcTex1 – ''Chlamydomonas reinhardtii'' – NMR<BR /> | [[1xdx]], [[1m9l]], [[1ds9]] - CrDYNC light chain TcTex1 – ''Chlamydomonas reinhardtii'' – NMR<BR /> | ||
| + | [[4ds1]] - yDYNC light chain + nucleoporin Nup129 peptide - yeast | ||
===Dynein intermediate chain=== | ===Dynein intermediate chain=== | ||
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===Dynein heavy chain=== | ===Dynein heavy chain=== | ||
| - | [[3qmz]] – | + | [[3qmz]] – yDYNC heavy chain + glutathione-S-transferase <BR /> |
[[3err]] - mDYNC heavy chain microtubule-binding domain/Ser-tRNA synthetase<br /> | [[3err]] - mDYNC heavy chain microtubule-binding domain/Ser-tRNA synthetase<br /> | ||
| - | [[3ay1]] - DYNC heavy chain – ''Dictyostelium discoideum''<br /> | + | [[3ay1]], [[3vkg]], [[3vkh]] - DYNC heavy chain – ''Dictyostelium discoideum''<br /> |
[[2rr7]] – CrDYNC microtubule-binding domain | [[2rr7]] – CrDYNC microtubule-binding domain | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 09:11, 7 June 2012
Dynein is a motor protein which walks along the microtubule toward its minus end, i.e. it is a minus-end directed motor. Dyneins are classified as cytoplasmic (DYNC) or axonemal. The Dyneins are composed of heavy, intermediate and light chains. For discussion of the DYNC inter mediate and light chains see: Dynein light and intermediate chain.
Contents |
3D Structures of Dynein
Update June 2012
Dynein light chain
3dvt, 3bri - DmDYNC light chain - Drosophila melanogaster
3dvh - DmDYNC light chain (mutant)
1rhw - DmDYNC light chain - NMR
1ygt - DmDYNC light chain TcTex1
2e8j, 2b95, 1z09 - hDYNC light chain 2A – human – NMR
2hz5 - hDYNC light chain 2A
2zqq - hDYNC light chain 2 + peptide
3p8m - hDYNC light chain 2 + GCN4
1y4o - mDYNC light chain 2A – mouse
1re6 - mDYNC light chain 2 – NMR
1pwj, 1pwk, 1f3c - rDYNC light chain 2 – rat – NMR
1f95, 1f96 - rDYNC light chain + peptide – NMR
3dvp, 3brl, 3e2b - DmDYNC light chain + peptide
1yo3 – DYNC light chain 1 – Plasmodium falciparum
1xdx, 1m9l, 1ds9 - CrDYNC light chain TcTex1 – Chlamydomonas reinhardtii – NMR
4ds1 - yDYNC light chain + nucleoporin Nup129 peptide - yeast
Dynein intermediate chain
3l7h – DmDYNC intermediate chain light chain roadblock
3l9k - DmDYNC intermediate chain light chain roadblock + intermediate chain
3fm7, 3glw, 2pg1, 2p2t - DmDYNC intermediate chain + light chain
Dynein heavy chain
3qmz – yDYNC heavy chain + glutathione-S-transferase
3err - mDYNC heavy chain microtubule-binding domain/Ser-tRNA synthetase
3ay1, 3vkg, 3vkh - DYNC heavy chain – Dictyostelium discoideum
2rr7 – CrDYNC microtubule-binding domain
